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Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition

Acivicin is a natural product with diverse biological activities. Several decades ago its clinical application in cancer treatment was explored but failed due to unacceptable toxicity. The causes behind the desired and undesired biological effects have never been elucidated and only limited informat...

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Detalles Bibliográficos
Autores principales:	Kreuzer, Johannes, Bach, Nina C., Forler, Daniel, Sieber, Stephan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285139/ https://www.ncbi.nlm.nih.gov/pubmed/25580214 http://dx.doi.org/10.1039/c4sc02339k

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