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Correlation of HOXD3 promoter hypermethylation with clinical and pathologic features in screening prostate biopsies

BACKGROUND: Molecular markers that can discriminate indolent cancers from aggressive ones may improve the management of prostate cancer and minimize unnecessary treatment. Aberrant DNA methylation is a common epigenetic event in cancers and HOXD3 promoter hypermethylation (H3PH) has been found in pr...

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Detalles Bibliográficos
Autores principales: Chen, Leonard N, Rubin, Rachel S, Othepa, Eugide, Cer, Caroline, Yun, Elizabeth, Agarwal, Raghunath P, Collins, Brian T, McGeagh, Kevin, Pahira, John, Bandi, Guarav, Kowalczyk, Keith, Kumar, Deepak, Dritschilo, Anatoly, Collins, Sean P, Bostwick, David G, Lynch, John H, Suy, Simeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285328/
https://www.ncbi.nlm.nih.gov/pubmed/24847526
http://dx.doi.org/10.1002/pros.22790