STAT3 paradoxically stimulates β-catenin expression but inhibits β-catenin function

Wnt signalling and the signal transducer and activator of transcription 3 (STAT3) are oncogenic signalling pathways which are deregulated in colorectal cancer (CRC). Here we investigated the interaction of these two pathways. Firstly, we investigated biochemical interaction by inhibiting STAT3 and β...

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Detalles Bibliográficos
Autores principales: Ibrahem, Salih, Al-Ghamdi, Saleh, Baloch, Kanwal, Muhammad, Belal, Fadhil, Wakkas, Jackson, Darryl, Nateri, Abdolrahman S, Ilyas, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285465/
https://www.ncbi.nlm.nih.gov/pubmed/25348333
http://dx.doi.org/10.1111/iep.12102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285465/
https://www.ncbi.nlm.nih.gov/pubmed/25348333
http://dx.doi.org/10.1111/iep.12102

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