Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

BACKGROUND: Gemcitabine is an analogue of deoxycytidine with activity against several solid tumors. In order to elucidate the mechanisms by which tumor cells become resistant to gemcitabine, we developed the resistant subline RL-G from the human follicular lymphoma cell line RL-7 by prolonged exposu...

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Detalles Bibliográficos
Autores principales: Galmarini, Carlos María, Clarke, Marilyn L, Jordheim, Lars, Santos, Cheryl L, Cros, Emeline, Mackey, John R, Dumontet, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC428575/
https://www.ncbi.nlm.nih.gov/pubmed/15157282
http://dx.doi.org/10.1186/1471-2210-4-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC428575/
https://www.ncbi.nlm.nih.gov/pubmed/15157282
http://dx.doi.org/10.1186/1471-2210-4-8

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