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Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene
BACKGROUND: Gemcitabine is an analogue of deoxycytidine with activity against several solid tumors. In order to elucidate the mechanisms by which tumor cells become resistant to gemcitabine, we developed the resistant subline RL-G from the human follicular lymphoma cell line RL-7 by prolonged exposu...
Autores principales: | Galmarini, Carlos María, Clarke, Marilyn L, Jordheim, Lars, Santos, Cheryl L, Cros, Emeline, Mackey, John R, Dumontet, Charles |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC428575/ https://www.ncbi.nlm.nih.gov/pubmed/15157282 http://dx.doi.org/10.1186/1471-2210-4-8 |
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