Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37

The effect of the anti-inflammatory cytokine interleukin-37 (IL-37) on host defense against Candida infections remains unknown. We assessed the role of IL-37 in a murine model of disseminated candidiasis using mice transgenic for human IL-37 (hIL-37Tg). Upon exposure to Candida albicans pseudohyphae...

Descripción completa

Detalles Bibliográficos
Autores principales: van de Veerdonk, Frank L., Gresnigt, Mark S., Oosting, Marije, van der Meer, Jos W. M., Joosten, Leo A. B., Netea, Mihai G., Dinarello, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285810/
https://www.ncbi.nlm.nih.gov/pubmed/25620965
http://dx.doi.org/10.3389/fmicb.2014.00762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285810/
https://www.ncbi.nlm.nih.gov/pubmed/25620965
http://dx.doi.org/10.3389/fmicb.2014.00762

Ejemplares similares