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The evolving genomic classification of lung cancer

EGFR gene mutations and ALK gene fusions are well-characterized molecular targets in NSCLC. Activating alterations in a variety of potential oncogenic driver genes have also been identified in NSCLC, including ROS1, RET, MET, HER2, and BRAF. Together with EGFR and ALK, these mutations account for ∼2...

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Detalles Bibliográficos
Autores principales: Shames, David S, Wistuba, Ignacio I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285848/
https://www.ncbi.nlm.nih.gov/pubmed/24114583
http://dx.doi.org/10.1002/path.4275