In-depth analysis of subclass-specific conformational preferences of IgG antibodies

IgG subclass-specific differences in biological function and in vitro stability are often referred to variations in the conformational flexibility, while this flexibility has rarely been characterized. Here, small-angle X-ray scattering data from IgG1, IgG2 and IgG4 antibodies, which were designed w...

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Detalles Bibliográficos
Autores principales: Tian, Xinsheng, Vestergaard, Bente, Thorolfsson, Matthias, Yang, Zhiru, Rasmussen, Hanne B., Langkilde, Annette E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285876/
https://www.ncbi.nlm.nih.gov/pubmed/25610623
http://dx.doi.org/10.1107/S205225251402209X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285876/
https://www.ncbi.nlm.nih.gov/pubmed/25610623
http://dx.doi.org/10.1107/S205225251402209X

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