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Pharmacokinetics and pharmacodynamics of levofloxacin injection in healthy Chinese volunteers and dosing regimen optimization

WHAT IS KNOWN AND OBJECTIVE: The pharmacokinetics (PK) and pharmacodynamics (PD) of levofloxacin were investigated following administration of levofloxacin injection in healthy Chinese volunteers for optimizing dosing regimen. METHODS: The PK study included single-dose (750 mg/150 mL) and multiple-d...

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Detalles Bibliográficos
Autores principales: Cao, G, Zhang, J, Wu, X, Yu, J, Chen, Y, Ye, X, Zhu, D, Zhang, Y, Guo, B, Shi, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285945/
https://www.ncbi.nlm.nih.gov/pubmed/23701411
http://dx.doi.org/10.1111/jcpt.12074