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Effects of imatinib mesylate on pulmonary allergic vasculitis in a murine model

OBJECTIVES: Imatinib mesylate (IM) is a potent and specific tyrosine inhibitor and has been reported to inhibit mesenchymal cell proliferation in pulmonary fibrosis. In the present study, we examine the effects of IM on vascular remodeling in a murine model of allergic vasculitis with eosinophil inf...

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Detalles Bibliográficos
Autores principales: Suzuki, Naomi, Sasaki, Nobuhito, Utsumi, Yu, Nagashima, Hiromi, Nakamura, Yutaka, Yamashita, Masahiro, Yamauchi, Kohei, Sawai, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285948/
https://www.ncbi.nlm.nih.gov/pubmed/23992268
http://dx.doi.org/10.1111/1756-185X.12075