Aging Alters Hepatic DNA Hydroxymethylation, as Measured by Liquid Chromatography/Mass Spectrometry

BACKGROUND: Aging is one of the most important risk factors for cancer. It appears that aberrant epigenetic changes might be a common driver of aging and cancer. Among them are changes in DNA methylation and DNA hydroxymethylation. The 5′ carbon of cytosines in CpG dinucleotides of DNA can be either...

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Detalles Bibliográficos
Autores principales: Tammen, Stephanie A., Dolnikowski, Gregory G., Ausman, Lynne M., Liu, Zhenhua, Kim, Kyong-chol, Friso, Simonetta, Choi, Sang-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285961/
https://www.ncbi.nlm.nih.gov/pubmed/25574465
http://dx.doi.org/10.15430/JCP.2014.19.4.301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285961/
https://www.ncbi.nlm.nih.gov/pubmed/25574465
http://dx.doi.org/10.15430/JCP.2014.19.4.301

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