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Altered brain protein expression profiles are associated with molecular neurological dysfunction in the PKU mouse model

Phenylketonuria (PKU), if not detected and treated in newborns, causes severe neurological dysfunction and cognitive and behavioral deficiencies. Despite the biochemical characterization of PKU, the molecular mechanisms underlying PKU-associated brain dysfunction remain poorly understood. The aim of...

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Detalles Bibliográficos
Autores principales: Imperlini, Esther, Orrù, Stefania, Corbo, Claudia, Daniele, Aurora, Salvatore, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286000/
https://www.ncbi.nlm.nih.gov/pubmed/24548049
http://dx.doi.org/10.1111/jnc.12683