A Bifurcated Proteoglycan Binding Small Molecule Carrier for siRNA Delivery

A wider application of siRNA- and miRNA- based therapeutics is restricted by the currently available delivery systems. We have designed a new type of small molecule carrier (SMoC) system for siRNA modeled to interact with cell surface proteoglycans. This bifurcated SMoC has similar affinity for the...

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Detalles Bibliográficos
Autores principales: Gooding, Matt, Adigbli, Derick, Edith Chan, A W, Melander, Roberta J, MacRobert, Alexander J, Selwood, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286013/
https://www.ncbi.nlm.nih.gov/pubmed/24472581
http://dx.doi.org/10.1111/cbdd.12295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286013/
https://www.ncbi.nlm.nih.gov/pubmed/24472581
http://dx.doi.org/10.1111/cbdd.12295

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