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Metabolomic Analysis of Akt1-Mediated Muscle Hypertrophy in Models of Diet-Induced Obesity and Age-Related Fat Accumulation

[Image: see text] Akt1 is a serine/threonine kinase that promotes cell growth and survival. Previously, Akt1 activation in a double transgenic (DTG) mouse model fed a high-fat/high-sucrose (HF/HS) diet was found to promote type IIb muscle growth and to lead to a significant reduction in obesity. Her...

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Detalles Bibliográficos
Autores principales: Cheng, Kian-Kai, Akasaki, Yuichi, Lecommandeur, Emmanuelle, Lindsay, Ross T., Murfitt, Steven, Walsh, Kenneth, Griffin, Julian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286153/
https://www.ncbi.nlm.nih.gov/pubmed/25231380
http://dx.doi.org/10.1021/pr500756u