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Saireito (TJ-114), a Japanese Traditional Herbal Medicine, Reduces 5-Fluorouracil-Induced Intestinal Mucositis in Mice by Inhibiting Cytokine-Mediated Apoptosis in Intestinal Crypt Cells

Clinical chemotherapy frequently causes intestinal mucositis as a side effect, which is accompanied by severe diarrhea. We recently showed that the cytokine-mediated apoptotic pathway might be important for the development of intestinal mucositis induced by 5-fluorouracil (5-FU). Saireito, the tradi...

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Detalles Bibliográficos
Autores principales: Kato, Shinichi, Hayashi, Shusaku, Kitahara, Yumeno, Nagasawa, Koyo, Aono, Hitomi, Shibata, Junichiro, Utsumi, Daichi, Amagase, Kikuko, Kadowaki, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286213/
https://www.ncbi.nlm.nih.gov/pubmed/25565296
http://dx.doi.org/10.1371/journal.pone.0116213