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Saireito (TJ-114), a Japanese Traditional Herbal Medicine, Reduces 5-Fluorouracil-Induced Intestinal Mucositis in Mice by Inhibiting Cytokine-Mediated Apoptosis in Intestinal Crypt Cells
Clinical chemotherapy frequently causes intestinal mucositis as a side effect, which is accompanied by severe diarrhea. We recently showed that the cytokine-mediated apoptotic pathway might be important for the development of intestinal mucositis induced by 5-fluorouracil (5-FU). Saireito, the tradi...
Autores principales: | Kato, Shinichi, Hayashi, Shusaku, Kitahara, Yumeno, Nagasawa, Koyo, Aono, Hitomi, Shibata, Junichiro, Utsumi, Daichi, Amagase, Kikuko, Kadowaki, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286213/ https://www.ncbi.nlm.nih.gov/pubmed/25565296 http://dx.doi.org/10.1371/journal.pone.0116213 |
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