Cargando…
A Cytosolic Juxtamembrane Interface Modulates Plexin A3 Oligomerization and Signal Transduction
Plexins (plxns) are transmembrane (TM) receptors involved in the guidance of vascular, lymphatic vessel, and neuron growth as well as cancer metastasis. Plxn signaling results in cytosolic GTPase-activating protein activity, and previous research implicates dimerization as important for activation o...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286236/ https://www.ncbi.nlm.nih.gov/pubmed/25565389 http://dx.doi.org/10.1371/journal.pone.0116368 |