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A Cytosolic Juxtamembrane Interface Modulates Plexin A3 Oligomerization and Signal Transduction

Plexins (plxns) are transmembrane (TM) receptors involved in the guidance of vascular, lymphatic vessel, and neuron growth as well as cancer metastasis. Plxn signaling results in cytosolic GTPase-activating protein activity, and previous research implicates dimerization as important for activation o...

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Detalles Bibliográficos
Autores principales: Barton, Rachael, Palacio, Danica, Iovine, M. Kathryn, Berger, Bryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286236/
https://www.ncbi.nlm.nih.gov/pubmed/25565389
http://dx.doi.org/10.1371/journal.pone.0116368