Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

Autophagy is a conserved process involved in lysosomal degradation of protein aggregates and damaged organelles. The role of autophagy in cancer is a topic of intense debate, and the underlying mechanism is still not clear. The hypoxia inducible factor 2α (HIF2α), an oncogenic transcription factor i...

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Detalles Bibliográficos
Autores principales: Liu, Xian-De, Yao, Jun, Tripathi, Durga Nand, Ding, Zhiyong, Xu, Yi, Sun, Mianen, Zhang, Jiangwei, Bai, Shanshan, German, Peter, Hoang, Anh, Zhou, Lijun, Jonasch, Darius, Zhang, Xuesong, Conti, Claudio J., Efstathiou, Eleni, Tannir, Nizar M, Eissa, N. Tony, Mills, Gordon B., Walker, Cheryl Lyn, Jonasch, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286517/
https://www.ncbi.nlm.nih.gov/pubmed/24998849
http://dx.doi.org/10.1038/onc.2014.199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286517/
https://www.ncbi.nlm.nih.gov/pubmed/24998849
http://dx.doi.org/10.1038/onc.2014.199

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