Polyoma small T antigen triggers cell death via mitotic catastrophe

Polyoma small T antigen (PyST), an early gene product of the polyoma virus, has been shown to cause cell death in a number of mammalian cells in a protein phosphatase 2A (PP2A)-dependent manner. In the current study, using a cell line featuring regulated expression of PyST, we found that PyST arrest...

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Detalles Bibliográficos
Autores principales: Fernando, Arun T Pores, Andrabi, Shaida, Cizmecioglu, Onur, Zhu, Cailei, Livingston, David M., Higgins, Jonathan M.G, Schaffhausen, Brian S, Roberts, Thomas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286542/
https://www.ncbi.nlm.nih.gov/pubmed/24998850
http://dx.doi.org/10.1038/onc.2014.192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286542/
https://www.ncbi.nlm.nih.gov/pubmed/24998850
http://dx.doi.org/10.1038/onc.2014.192

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