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A conserved P-loop anchor limits the structural dynamics that mediate nucleotide dissociation in EF-Tu
The phosphate-binding loop (P-loop) is a conserved sequence motif found in mononucleotide-binding proteins. Little is known about the structural dynamics of this region and its contribution to the observed nucleotide binding properties. Understanding the underlying design principles is of great inte...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286738/ https://www.ncbi.nlm.nih.gov/pubmed/25566871 http://dx.doi.org/10.1038/srep07677 |