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A conserved P-loop anchor limits the structural dynamics that mediate nucleotide dissociation in EF-Tu

The phosphate-binding loop (P-loop) is a conserved sequence motif found in mononucleotide-binding proteins. Little is known about the structural dynamics of this region and its contribution to the observed nucleotide binding properties. Understanding the underlying design principles is of great inte...

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Detalles Bibliográficos
Autores principales: Mercier, Evan, Girodat, Dylan, Wieden, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286738/
https://www.ncbi.nlm.nih.gov/pubmed/25566871
http://dx.doi.org/10.1038/srep07677