The tyrosine kinase Itk suppresses CD8(+) memory T cell development in response to bacterial infection

Vaccine efficacy depends on strong long-term development of immune memory and the formation of memory CD8(+) T cells is critical for recall responses to infection. Upon antigen recognition by naïve T cells, the strength of the TcR signal influences the subsequent effector and memory cells differenti...

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Detalles Bibliográficos
Autores principales: Huang, Fei, Huang, Weishan, Briggs, Jessica, Chew, Tina, Bai, Yuting, Deol, Simrita, August, Avery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286740/
https://www.ncbi.nlm.nih.gov/pubmed/25567129
http://dx.doi.org/10.1038/srep07688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286740/
https://www.ncbi.nlm.nih.gov/pubmed/25567129
http://dx.doi.org/10.1038/srep07688

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