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The tyrosine kinase Itk suppresses CD8(+) memory T cell development in response to bacterial infection
Vaccine efficacy depends on strong long-term development of immune memory and the formation of memory CD8(+) T cells is critical for recall responses to infection. Upon antigen recognition by naïve T cells, the strength of the TcR signal influences the subsequent effector and memory cells differenti...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286740/ https://www.ncbi.nlm.nih.gov/pubmed/25567129 http://dx.doi.org/10.1038/srep07688 |