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Atractylochromene Is a Repressor of Wnt/β-Catenin Signaling in Colon Cancer Cells
Wnt/β-catenin signaling pathway was mutated in about 90% of the sporadic and hereditary colorectal cancers. The abnormally activated β-catenin increases the cancer cell proliferation, differentiation and metastasis through increasing the expression of its oncogenic target genes. In this study, we id...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286746/ https://www.ncbi.nlm.nih.gov/pubmed/25593640 http://dx.doi.org/10.4062/biomolther.2014.095 |