Atractylochromene Is a Repressor of Wnt/β-Catenin Signaling in Colon Cancer Cells

Wnt/β-catenin signaling pathway was mutated in about 90% of the sporadic and hereditary colorectal cancers. The abnormally activated β-catenin increases the cancer cell proliferation, differentiation and metastasis through increasing the expression of its oncogenic target genes. In this study, we id...

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Detalles Bibliográficos
Autores principales: Shim, Ah-Ram, Dong, Guang-zhi, Lee, Hwa Jin, Ryu, Jae-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286746/
https://www.ncbi.nlm.nih.gov/pubmed/25593640
http://dx.doi.org/10.4062/biomolther.2014.095

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