Cargando…

The Histone Deacetylase Inhibitor Trichostatin A Sensitizes Human Renal Carcinoma Cells to TRAIL-Induced Apoptosis through Down-Regulation of c-FLIP(L)

Histone acetylation plays a critical role in the regulation of transcription by altering the structure of chromatin, and it may influence the resistance of some tumor cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) by regulating the gene expression of components of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Min Ho, Park, Cheol, Kwon, Taek Kyu, Kim, Gi-Young, Kim, Wun-Jae, Hong, Sang Hoon, Yoo, Young Hyun, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286747/
https://www.ncbi.nlm.nih.gov/pubmed/25593641
http://dx.doi.org/10.4062/biomolther.2014.092