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7α-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells

We investigated the question of whether 7-oxygenated cholesterol derivatives could affect inflammatory and/or immune responses in atherosclerosis by examining their effects on expression of IL-23 in monocytic cells. 7α-Hydroxycholesterol (7αOHChol) induced transcription of the TLR6 gene and elevated...

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Detalles Bibliográficos
Autores principales: Seo, Hyun Chul, Kim, Sun-Mi, Eo, Seong-Kug, Rhim, Byung-Yong, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286754/
https://www.ncbi.nlm.nih.gov/pubmed/25593648
http://dx.doi.org/10.4062/biomolther.2014.067