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β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure

β2-AR activation increases the risk of sudden cardiac death (SCD) in heart failure (HF) patients. Non-selective β-AR blockers have greater benefits on survival than selective β1-AR blockers in chronic HF patients, indicating that β2-AR activation contributes to SCD in HF. This study investigated the...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Yuan, Jiamin, Qian, Zhiyong, Zhang, Xiwen, Chen, Yanhong, Hou, Xiaofeng, Zou, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286790/
https://www.ncbi.nlm.nih.gov/pubmed/25567365
http://dx.doi.org/10.1038/srep07681