Heterologous Aggregates Promote De Novo Prion Appearance via More than One Mechanism

Prions are self-perpetuating conformational variants of particular proteins. In yeast, prions cause heritable phenotypic traits. Most known yeast prions contain a glutamine (Q)/asparagine (N)-rich region in their prion domains. [PSI(+)], the prion form of Sup35, appears de novo at dramatically enhan...

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Detalles Bibliográficos
Autores principales: Arslan, Fatih, Hong, Joo Y., Kanneganti, Vydehi, Park, Sei-Kyoung, Liebman, Susan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287349/
https://www.ncbi.nlm.nih.gov/pubmed/25568955
http://dx.doi.org/10.1371/journal.pgen.1004814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287349/
https://www.ncbi.nlm.nih.gov/pubmed/25568955
http://dx.doi.org/10.1371/journal.pgen.1004814

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