Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD

Chronic Obstructive Pulmonary Disease (COPD) is a complex disease. Genetic, epigenetic, and environmental factors are known to contribute to COPD risk and disease progression. Therefore we developed a systematic approach to identify key regulators of COPD that integrates genome-wide DNA methylation,...

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Detalles Bibliográficos
Autores principales: Yoo, Seungyeul, Takikawa, Sachiko, Geraghty, Patrick, Argmann, Carmen, Campbell, Joshua, Lin, Luan, Huang, Tao, Tu, Zhidong, Feronjy, Robert, Spira, Avrum, Schadt, Eric E., Powell, Charles A., Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287352/
https://www.ncbi.nlm.nih.gov/pubmed/25569234
http://dx.doi.org/10.1371/journal.pgen.1004898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287352/
https://www.ncbi.nlm.nih.gov/pubmed/25569234
http://dx.doi.org/10.1371/journal.pgen.1004898

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