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Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction
BACKGROUND: Natural killer (NK) cells play a key role in non-specific immune response in different cancers, including pancreatic cancer. However the anti-tumor effect of NK cells decreases during pancreatic cancer progression. The regulatory pathways by which NK cells facilitate tumor immune escape...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287420/ https://www.ncbi.nlm.nih.gov/pubmed/25274283 http://dx.doi.org/10.1186/1471-2407-14-738 |