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Sumoylation Influences DNA Break Repair Partly by Increasing the Solubility of a Conserved End Resection Protein

Protein modifications regulate both DNA repair levels and pathway choice. How each modification achieves regulatory effects and how different modifications collaborate with each other are important questions to be answered. Here, we show that sumoylation regulates double-strand break repair partly b...

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Detalles Bibliográficos
Autores principales: Sarangi, Prabha, Steinacher, Roland, Altmannova, Veronika, Fu, Qiong, Paull, Tanya T., Krejci, Lumir, Whitby, Matthew C., Zhao, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287433/
https://www.ncbi.nlm.nih.gov/pubmed/25569253
http://dx.doi.org/10.1371/journal.pgen.1004899