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Sumoylation Influences DNA Break Repair Partly by Increasing the Solubility of a Conserved End Resection Protein
Protein modifications regulate both DNA repair levels and pathway choice. How each modification achieves regulatory effects and how different modifications collaborate with each other are important questions to be answered. Here, we show that sumoylation regulates double-strand break repair partly b...
Autores principales: | Sarangi, Prabha, Steinacher, Roland, Altmannova, Veronika, Fu, Qiong, Paull, Tanya T., Krejci, Lumir, Whitby, Matthew C., Zhao, Xiaolan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287433/ https://www.ncbi.nlm.nih.gov/pubmed/25569253 http://dx.doi.org/10.1371/journal.pgen.1004899 |
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