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Elevated Mutation Rate during Meiosis in Saccharomyces cerevisiae

Mutations accumulate during all stages of growth, but only germ line mutations contribute to evolution. While meiosis contributes to evolution by reassortment of parental alleles, we show here that the process itself is inherently mutagenic. We have previously shown that the DNA synthesis associated...

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Detalles Bibliográficos
Autores principales: Rattray, Alison, Santoyo, Gustavo, Shafer, Brenda, Strathern, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287439/
https://www.ncbi.nlm.nih.gov/pubmed/25569256
http://dx.doi.org/10.1371/journal.pgen.1004910