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Nur1 Dephosphorylation Confers Positive Feedback to Mitotic Exit Phosphatase Activation in Budding Yeast

Substrate dephosphorylation by the cyclin-dependent kinase (Cdk)-opposing phosphatase, Cdc14, is vital for many events during budding yeast mitotic exit. Cdc14 is sequestered in the nucleolus through inhibitory binding to Net1, from which it is released in anaphase following Net1 phosphorylation. In...

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Detalles Bibliográficos
Autores principales: Godfrey, Molly, Kuilman, Thomas, Uhlmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287440/
https://www.ncbi.nlm.nih.gov/pubmed/25569132
http://dx.doi.org/10.1371/journal.pgen.1004907