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Ribose 5-Phosphate Isomerase B Knockdown Compromises Trypanosoma brucei Bloodstream Form Infectivity

Ribose 5-phosphate isomerase is an enzyme involved in the non-oxidative branch of the pentose phosphate pathway, and catalyzes the inter-conversion of D-ribose 5-phosphate and D-ribulose 5-phosphate. Trypanosomatids, including the agent of African sleeping sickness namely Trypanosoma brucei, have a...

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Detalles Bibliográficos
Autores principales: Loureiro, Inês, Faria, Joana, Clayton, Christine, Macedo-Ribeiro, Sandra, Santarém, Nuno, Roy, Nilanjan, Cordeiro-da-Siva, Anabela, Tavares, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287489/
https://www.ncbi.nlm.nih.gov/pubmed/25568941
http://dx.doi.org/10.1371/journal.pntd.0003430