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FastMG: a simple, fast, and accurate maximum likelihood procedure to estimate amino acid replacement rate matrices from large data sets

BACKGROUND: Amino acid replacement rate matrices are a crucial component of many protein analysis systems such as sequence similarity search, sequence alignment, and phylogenetic inference. Ideally, the rate matrix reflects the mutational behavior of the actual data under study; however, estimating...

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Detalles Bibliográficos
Autores principales: Dang, Cuong Cao, Le, Vinh Sy, Gascuel, Olivier, Hazes, Bart, Le, Quang Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287512/
https://www.ncbi.nlm.nih.gov/pubmed/25344302
http://dx.doi.org/10.1186/1471-2105-15-341