Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets

BACKGROUND: Human pancreatic islet structure poses challenges to investigations that require specific modulation of gene expression. Yet dissociation of islets into individual cells destroys cellular interactions important to islet physiology. Approaches that improve transient targeting of gene expr...

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Detalles Bibliográficos
Autores principales: Tamaki, Stanley, Nye, Christopher, Slorach, Euan, Scharp, David, Blau, Helen M, Whiteley, Phyllis E, Pomerantz, Jason H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287515/
https://www.ncbi.nlm.nih.gov/pubmed/25305068
http://dx.doi.org/10.1186/1472-6750-14-86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287515/
https://www.ncbi.nlm.nih.gov/pubmed/25305068
http://dx.doi.org/10.1186/1472-6750-14-86

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