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ASAR15, A cis-Acting Locus that Controls Chromosome-Wide Replication Timing and Stability of Human Chromosome 15

DNA replication initiates at multiple sites along each mammalian chromosome at different times during each S phase, following a temporal replication program. We have used a Cre/loxP-based strategy to identify cis-acting elements that control this replication-timing program on individual human chromo...

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Detalles Bibliográficos
Autores principales: Donley, Nathan, Smith, Leslie, Thayer, Mathew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287527/
https://www.ncbi.nlm.nih.gov/pubmed/25569254
http://dx.doi.org/10.1371/journal.pgen.1004923