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Aptamer-Based Detection of Disease Biomarkers in Mouse Models for Chagas Drug Discovery

Drug discovery initiatives, aimed at Chagas treatment, have been hampered by the lack of standardized drug screening protocols and the absence of simple pre-clinical assays to evaluate treatment efficacy in animal models. In this study, we used a simple Enzyme Linked Aptamer (ELA) assay to detect T....

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Detalles Bibliográficos
Autores principales: de Araujo, Fernanda Fortes, Nagarkatti, Rana, Gupta, Charu, Marino, Ana Paula, Debrabant, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287562/
https://www.ncbi.nlm.nih.gov/pubmed/25569299
http://dx.doi.org/10.1371/journal.pntd.0003451