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Aptamer-Based Detection of Disease Biomarkers in Mouse Models for Chagas Drug Discovery
Drug discovery initiatives, aimed at Chagas treatment, have been hampered by the lack of standardized drug screening protocols and the absence of simple pre-clinical assays to evaluate treatment efficacy in animal models. In this study, we used a simple Enzyme Linked Aptamer (ELA) assay to detect T....
Autores principales: | de Araujo, Fernanda Fortes, Nagarkatti, Rana, Gupta, Charu, Marino, Ana Paula, Debrabant, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287562/ https://www.ncbi.nlm.nih.gov/pubmed/25569299 http://dx.doi.org/10.1371/journal.pntd.0003451 |
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