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In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni

Morbidity and mortality caused by schistosomiasis are serious public health problems in developing countries. Because praziquantel is the only drug in therapeutic use, the risk of drug resistance is a concern. In the search for new schistosomicidal drugs, we performed a target-based chemogenomics sc...

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Detalles Bibliográficos
Autores principales: Neves, Bruno J., Braga, Rodolpho C., Bezerra, José C. B., Cravo, Pedro V. L., Andrade, Carolina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287566/
https://www.ncbi.nlm.nih.gov/pubmed/25569258
http://dx.doi.org/10.1371/journal.pntd.0003435