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In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni
Morbidity and mortality caused by schistosomiasis are serious public health problems in developing countries. Because praziquantel is the only drug in therapeutic use, the risk of drug resistance is a concern. In the search for new schistosomicidal drugs, we performed a target-based chemogenomics sc...
Autores principales: | Neves, Bruno J., Braga, Rodolpho C., Bezerra, José C. B., Cravo, Pedro V. L., Andrade, Carolina H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287566/ https://www.ncbi.nlm.nih.gov/pubmed/25569258 http://dx.doi.org/10.1371/journal.pntd.0003435 |
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