Cargando…

Different Infectivity of HIV-1 Strains Is Linked to Number of Envelope Trimers Required for Entry

HIV-1 enters target cells by virtue of envelope glycoprotein trimers that are incorporated at low density in the viral membrane. How many trimers are required to interact with target cell receptors to mediate virus entry, the HIV entry stoichiometry, still awaits clarification. Here, we provide esti...

Descripción completa

Detalles Bibliográficos
Autores principales: Brandenberg, Oliver F., Magnus, Carsten, Rusert, Peter, Regoes, Roland R., Trkola, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287578/
https://www.ncbi.nlm.nih.gov/pubmed/25569556
http://dx.doi.org/10.1371/journal.ppat.1004595