Viral Activation of MK2-hsp27-p115RhoGEF-RhoA Signaling Axis Causes Cytoskeletal Rearrangements, P-body Disruption and ARE-mRNA Stabilization

Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious cause of several AIDS-related cancers, including the endothelial cell (EC) neoplasm Kaposi's sarcoma (KS). KSHV-infected ECs secrete abundant host-derived pro-inflammatory molecules and angiogenic factors that contribute to t...

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Detalles Bibliográficos
Autores principales: Corcoran, Jennifer A., Johnston, Benjamin P., McCormick, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287613/
https://www.ncbi.nlm.nih.gov/pubmed/25569678
http://dx.doi.org/10.1371/journal.ppat.1004597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287613/
https://www.ncbi.nlm.nih.gov/pubmed/25569678
http://dx.doi.org/10.1371/journal.ppat.1004597

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