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Beta cell regeneration after single-round immunological destruction in a mouse model

AIMS/HYPOTHESIS: Achieving a better understanding of beta cell regeneration after immunological destruction is crucial for the development of immunotherapy approaches for type 1 diabetes. In previous type 1 diabetes models, sustained immune activation eliminates regenerating beta cells, thus limitin...

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Detalles Bibliográficos
Autores principales: Tonne, Jason M., Sakuma, Toshie, Munoz-Gomez, Miguel, El Khatib, Moustafa, Barry, Michael A., Kudva, Yogish C., Ikeda, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287683/
https://www.ncbi.nlm.nih.gov/pubmed/25338552
http://dx.doi.org/10.1007/s00125-014-3416-4