Lenticular cytoprotection, part 2: Link between glycogen synthase kinase-3β, epithelial to mesenchymal transition, and mitochondrial depolarization

PURPOSE: The inhibition of GSK-3β blocks mitochondrial membrane permeability transition (mMPT) for HLE-B3 cells in atmospheric oxygen. GSK-3β, as part of a multifactorial complex, also regulates nuclear levels of β-catenin, a known coordinator of cell survival and adhesion. The purpose of these stud...

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Detalles Bibliográficos
Autores principales: Neelam, Sudha, Brooks, Morgan M., Cammarata, Patrick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287703/
https://www.ncbi.nlm.nih.gov/pubmed/25593505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287703/
https://www.ncbi.nlm.nih.gov/pubmed/25593505

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