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Discovery of a Heparan Sulfate 3-O-Sulfation Specific Peeling Reaction

[Image: see text] Heparan sulfate (HS) 3-O-sulfation determines the binding specificity of HS/heparin for antithrombin III and plays a key role in herpes simplex virus (HSV) infection. However, the low natural abundance of HS 3-O-sulfation poses a serious challenge for functional studies other than...

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Detalles Bibliográficos
Autores principales: Huang, Yu, Mao, Yang, Zong, Chengli, Lin, Cheng, Boons, Geert-Jan, Zaia, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287833/
https://www.ncbi.nlm.nih.gov/pubmed/25486437
http://dx.doi.org/10.1021/ac503248k