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IRS1 gene polymorphisms Gly972Arg and Ala513Pro are not associated with insulin resistance and type 2 diabetes risk in non-obese Turkish population

Insulin receptor substrate 1 (IRS1), plays a critical role in insulin signaling and its control has an important place in the development of insulin resistance. The tyrosine phosphorylation of IRS1 serves as docking molecules for downstream effectors such as Phosphatidylinositol 3-kinase and phospho...

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Detalles Bibliográficos
Autores principales: Arikoglu, Hilal, Aksoy Hepdogru, Melda, Erkoc Kaya, Dudu, Asik, Aycan, Ipekci, Suleyman Hilmi, Iscioglu, Funda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287848/
https://www.ncbi.nlm.nih.gov/pubmed/25606440
http://dx.doi.org/10.1016/j.mgene.2014.07.008