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mtDNA G10398A variation provides risk to type 2 diabetes in population group from the Jammu region of India

Mitochondrion plays an integral role in glucose metabolism and insulin secretion. Mitochondrial electron-transport chain (ETC) is involved in adenosine triphosphate (ATP) generation and ATP mediated insulin secretion in pancreatic β-cells. β-cell dysfunction is a critical component in the pathogenes...

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Detalles Bibliográficos
Autores principales: Sharma, Varun, Sharma, Indu, Singh, Vishav Pratap, Verma, Sonali, Pandita, Anil, Singh, Vinod, Rai, Ekta, Sharma, Swarkar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287871/
https://www.ncbi.nlm.nih.gov/pubmed/25606409
http://dx.doi.org/10.1016/j.mgene.2014.02.003