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mtDNA G10398A variation provides risk to type 2 diabetes in population group from the Jammu region of India
Mitochondrion plays an integral role in glucose metabolism and insulin secretion. Mitochondrial electron-transport chain (ETC) is involved in adenosine triphosphate (ATP) generation and ATP mediated insulin secretion in pancreatic β-cells. β-cell dysfunction is a critical component in the pathogenes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287871/ https://www.ncbi.nlm.nih.gov/pubmed/25606409 http://dx.doi.org/10.1016/j.mgene.2014.02.003 |